The Pfizer Clinical Research Unit in New Haven is conducting a trial of an oral study drug for heart failure. The purpose of this study is to assess the effects of multiple doses of the study drug when given to healthy volunteers and involves MRS scanning (similar to an MRI).
Heart failure happens when the heart cannot pump enough blood and oxygen throughout the body. This is often the result of an underlying illness and can be a serious or even life-threatening condition. There is currently no cure for heart failure and patients are in need of effective treatment options.
Read more about this study below and see how you can help patients as a healthy volunteer.
Who may participate
You never know who you might help when you volunteer for a clinical trial, but you will know that you made a difference for patients around the world.
This study is seeking healthy adult volunteers, meaning that the participants will not have the condition being studied and are in overall good health. In addition to the criteria listed, participants must meet the following requirements:
- Willing to take a study drug
- Able to meet criteria for MRS/MRI safety – if you’re unsure, we will assess this with you prior to your appointment
- Able to travel to the New Haven CRU for all study visits*
*participants may be eligible to receive a bonus for travel, ask our staff for details
**females must be unable to bear children
There are other requirements for participation in this study. The study staff will explain these to you during the screening process.
Do you know someone who may meet these requirements? Refer a friend and you may be eligible to receive a bonus.
Condition
Healthy
Age
18-65 years
Sex
All sexes**
Referral bonus
Up to $150
Each clinical study has its own guidelines for who can participate, called eligibility criteria. However, only the research study staff can determine if you qualify to enroll in the study.
What to expect
If this study may be a fit for you, you’ll be invited to a screening visit at our facility in New Haven, CT. If you qualify for the study, there may be a period of up to 28 days before dosing.
If you choose to participate, you will stay at our facility for 17 consecutive overnights. During your stay, you will have 2 scheduled MRS scans, which are a type of imaging scan. These are similar to an MRI and use the same machine but look at different things in your body. At each scan, you will receive a substance via an IV catheter called Carbon-13 which is non-radioactive and is used to see metabolic reactions during the MRS scan.
Your first scan is about 2 days after you arrive at the unit for admission. The day after your first MRS scan, you will begin receiving once-daily doses of the study drug or a placebo in the morning for up to 14 total doses. All doses are given as tablets to swallow. Your second MRS scan will occur on the last day of dosing. You will be able to leave the unit after procedures are completed and will return a week later for a follow-up visit.
Throughout the study, staff will closely monitor your health status and collect data, such as the levels of the study drug in your blood.
Required overnight stays
17 consecutive nights
Long-term follow up
1 follow-up visit + 1 phone call
How long is this study?
About 45 days
Compensation
Up to $6,525 upon completion of the study
All of the study procedures will be clearly explained to you during screening and can be viewed by downloading the informed consent form.
The PCRU Loyalty Program has arrived!
Our new Loyalty Program offers unique tiered gifts for new and returning participants.
Interested in participating?
Complete and submit this form, and a Pfizer New Haven Clinical Research Unit (PCRU) representative will contact you.
You may also call 1-800-254-6398 and speak with a PCRU representative to learn more.
For Japanese language assistance only, please call 1-833-711-9984.
The personal data gathered here will be collected, processed, and maintained in a confidential manner. Your information will be stored in our research unit’s database. We may use this information to invite you to participate in current and future clinical studies at the PCRU. You will have full access to your records at the Pfizer New Haven Clinical Research Unit and the opportunity to correct them if necessary.